Network Pharmacology and Molecular Docking Analysis on Molecular Targets and Mechanisms of Bushen Hugu Decoction in the Treatment of Malignant Tumor Bone Metastases

Table 1

Major active components of BHD from TCMSP dataset.

Herb	Mark	Component
Cuscutae Semen	CS1	Sesamin
	CS2	NSC63551
	CS3	Isorhamnetin
	CS4	Campest-5-en-3beta-ol
	CS5	Isofucosterol
	CS6	Matrine
	CS7	Sophranol
	CS8	CLR
	A1	Beta-sitosterol
	A2	Kaempferol
	A3	Quercetin
Rehmanniae Radix Praeparata	B1	Sitosterol
	B2	Stigmasterol
Eucommiae Cortex	EC1	Mairin
	EC2	Erythraline
	EC3	3-Beta-hydroxymethyllenetanshiquinone
	EC4	Eucommin A
	EC5	(-)-Tabernaemontana
	EC6	Cyclopamine
	EC7	Dehydrodiconiferyl alcohol 4, gamma-di-O-beta-D-glucopyranoside_qt
	EC8	GBGB
	EC9	Helenalin
	EC10	4-[(2S,3R)-5-[(E)-3-Hydroxyprop-1-enyl]-7-methoxy-3-methylol-2,3-dihydrobenzofuran-2-yl]-2-methoxy-phenol
	EC11	Beta-carotene
	EC12	(E)-3-[4-[(1R,2R)-2-Hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-1-methylol-ethoxy]-3-methoxy-phenyl]acrolein
	EC13	Syringetin
	A1	Beta-sitosterol
	A2	Kaempferol
	A3	Quercetin
Dipsaci Radix	DRD1	Gentisin
	DRD2	Japonine
	DRD3	Sylvestroside III
	DRD4	Sylvestroside III_qt
	A1	Beta-sitosterol
	B1	Sitosterol
Cistanches Herba	CH1	Arachidonate
	CH2	Suchilactone
	CH3	Marckine
	A1	Beta-sitosterol
	A3	Quercetin
Drynariae Rhizoma	DR1	22-Stigmasten-3-one
	DR2	Marioside_qt
	DR3	Cycloartenone
	DR4	Digallate
	DR5	Cyclolaudenol
	DR6	Cyclolaudenol acetate
	DR7	Eriodictyol
	DR8	Eriodyctiol (flavanone)
	DR9	Luteolin
	DR10	Xanthogalenol
	DR11	(2R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
	DR12	Naringenin
	DR13	Aureusidin
	A1	Beta-sitosterol
	B2	Stigmasterol
Sinapis Semen	SS1	Sinoacutine
	SS2	2-(2-Phenylethyl)-6-[[(5S,6R,7R,8S)-5,6,7-trihydroxy-4-keto-2-(2-phenylethyl)-5,6,7,8-tetrahydrochromen-8-yl]oxy]chromone
	SS3	Uniflex BYO
Radix Angelicae Biseratae	RAB1	Angelicone
	RAB2	Nodakenin
	A1	Beta-sitosterol