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miRNA | Cell types | Functions | References |
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miR-21 | Macrophages | Changes in the polarity of macrophages | [11] |
miR-125a | HSCs | Regulates the survival of HSCs | [15] |
miR-126 | HSCs | Inhibits the cell cycle | [16] |
miR-127 | Macrophages | Changes in the polarity of macrophages | [13] |
miR-124 | Macrophages | Promotes the differentiation of M1 macrophages | [14] |
miR-152 | NK cell | Upregulates the activity of NK cells | [8] |
miR-29 | NK cell | Regulates NK cells indirectly through B7-H3 | [19] |
miR-142 | DC | Enhances the activation of inflammatory factors | [22] |
miR-155 | DC | Suppresses DC-mediated immune response | [23] |
miR-28 | T cell | 3-UTR binds directly to PD-1 | [32] |
miR-195 | T cell | Regulates CD+4 T cell activation by CCDC88C | [34] |
miR-448 | T cell | Inhibits IDO1 | [36] |
miR-181a | T cell | Control TCR signal | [38] |
miR-126 | T cell | Acts on IRS-1, regulates T cell activation | [39] |
miR-150 | B cell | Acts on BCR, controls B cell differentiation | [40] |
miR-1 | CAF | Regulates FOXO3a/VEGF/CCL2 | [45] |
miR-206 | CAF | Regulates FOXO3a/VEGF/CCL2 | [45] |
miR-31 | CAF | Regulates FOXO3a/VEGF/CCL2 | [45] |
miR-186 | NK cell | Suppresses immune escape | [59] |
miR-142-5p | T cell | Overexpression inhibits the PD-1/PD-L1 pathway | [107] |
miR-21 | MDSC | Activates MDSC amplification | [57] |
miR-138 | T cell | Inhibits the expression of CTLA-4 and PD-1 | [67] |
miR-374b | T cell | Downregulates PD-1 | [68] |
miR-155 | T cell | Inhibits PD-1 and CTLA-4 | [71] |
miR-1207-5p | CHO cell | Binding to B7-H4 3-UTR allele | [77] |
miR-24 | CHO cell | Associated with B7-H2 | [87] |
miR-172-92 | CAR-T cell | Enhances CAR-T cell antigenicity | [96] |
miR-153 | CAR-T cell | Inhibits IDO1, enhances cell lethality | [104] |
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