Research Article
Expression of Matrix Metalloproteinase-7 Predicts Poor Prognosis in Gastric Cancer
Table 4
The association of MMP-7 status and clinicopathological outcome of gastric cancer.
| Gastric mucosal pathology | MMP-7 status | OR; 95% CI | value | Low expression () | High expression () |
| Lymphatic invasion (%) | | | | | Absent | 99 (84.61) | 64 (22.61) | 0.27 (0.16-0.72) | 0.022 | Present | 18 (15.38) | 219 (77.38) | 8.17 (4.47-12.39) | 0.017 | Vascular invasion (%) | | | | | Absent | 89 (76.06) | 52 (18.37) | 0.58 (0.21-0.87) | 0.036 | Present | 28 (23.93) | 231 (81.62) | 6.16 (4.26-9.89) | 0.024 | Histologic type (%) | | | | | Undifferentiated | 35 (29.91) | 189 (66.78) | 2.46 (1.31-4.52) | 0.014 | Pathological TNM stage (%) | | | | | IV | 32 (27.35) | 144 (50.88) | 1.48 (1.08-3.08) | 0.047 | CEA (%) | | | | | < 5.0 (ng/ml) | 101 (86.32) | 67 (23.67) | 0.47 (0.28-0.88) | 0.041 | ≥ 5.0 (ng/ml) | 16 (13.67) | 216 (76.32) | 5.96 (2.12-8.12) | 0.026 |
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Multivariate regression model analysis. considered as statistically significant. |