Research Article

Expression of Matrix Metalloproteinase-7 Predicts Poor Prognosis in Gastric Cancer

Table 4

The association of MMP-7 status and clinicopathological outcome of gastric cancer.

Gastric mucosal pathologyMMP-7 statusOR; 95% CI value
Low expression ()High expression ()

Lymphatic invasion (%)
Absent99 (84.61)64 (22.61)0.27 (0.16-0.72)0.022
Present18 (15.38)219 (77.38)8.17 (4.47-12.39)0.017
Vascular invasion (%)
Absent89 (76.06)52 (18.37)0.58 (0.21-0.87)0.036
Present28 (23.93)231 (81.62)6.16 (4.26-9.89)0.024
Histologic type (%)
Undifferentiated35 (29.91)189 (66.78)2.46 (1.31-4.52)0.014
Pathological TNM stage (%)
IV32 (27.35)144 (50.88)1.48 (1.08-3.08)0.047
CEA (%)
< 5.0 (ng/ml)101 (86.32)67 (23.67)0.47 (0.28-0.88)0.041
≥ 5.0 (ng/ml)16 (13.67)216 (76.32)5.96 (2.12-8.12)0.026

Multivariate regression model analysis. considered as statistically significant.