Review Article

Efficacy and Safety of Roxadustat in Patients with Chronic Kidney Disease: An Updated Meta-Analysis of Randomized Controlled Trials including 6,518 Patients

Table 2

Mean change from baseline in iron parameter and lipid levels in DD study.

Parameter value for heterogeneity (, )SMD/WMD (95% CI) value

Hepcidin
-0.12 (-0.39, 0.15)
Iron
1.43 (0.31, 2.55)
Transferrin
3.77 (0.04, 7.50)
Soluble transferrin receptor
0.09 (-0.61, 0.79)
Total iron-binding capacity
2.06 (0.91, 3.22)
Total cholesterol
-0.36 (-1.35, 0.62)
Ferritin
21.33 (3.04, 39.62)
Transferrin saturationpā€‰=ā€‰0.46
4.17 (3.90, 4.45)
LDL-cholesterol
-0.64 (-0.73, -0.55)
Triglycerides
-0.09 (-0.39, 0.21)

LDL-cholesterol: low-density lipoprotein cholesterol.