Review Article

Efficacy and Safety of Roxadustat in Patients with Chronic Kidney Disease: An Updated Meta-Analysis of Randomized Controlled Trials including 6,518 Patients

Table 3

Mean change from baseline in iron parameter and lipid levels in NDD study.

Parameter value for heterogeneity (, )SMD/WMD (95% CI) value

Hepcidin
-1.56 (-2.63, -0.50)
Iron
-0.06 (-0.29, 0.18)
Transferrin
1.80 (1.53, 2.06)
Total iron-binding capacity
1.62 (1.39, 1.86)
Total cholesterol
-0.88 (-1.68, -0.09)
Ferritin
-52.68 (-62.68, -42.67)
Transferrin saturation
-5.57 (-7.47, -3.68)
LDL-cholesterol
-0.85 (-1.37, -0.34)

LDL-cholesterol: low-density lipoprotein cholesterol.