Fetal Fibronectin as a Predictor of Preterm Delivery: A Nigerian Cohort Study

Table 5

Diagnostic performance of fetal fibronectin.

(a) Symptomatic (preterm labour)

fFN test	Preterm delivery	Term delivery	Total
Positive	39	8	47
Negative	6	43	49
Total	45	51	96

(b)

Sensitivity	86.67% (95% CI, 73.21% -94.95%)
Specificity	84.31% (95% CI, 71.41% -92.98%)
PPV	82.98% ((95% CI, 71.86% -90.30%)
NPV	87.76% (95% CI, 77.12% -93.84%)
LR+	5.53% (95% CI, 2.89 – 10.55%)
LR-	0.16 (95% CI, 0.07 - 0.34)
RR	6.77 (95% CI, 3.16 – 14.50)
Accuracy	85.42%(95% CI, 76.74% -91.79%)

(c) Asymptomatic

fFN test	Preterm delivery	Term delivery	Total
Positive	12	1	13
Negative	4	79	83
Total	16	80	96

(d)

Sensitivity	75.00% (95% CI, 47.62% -92.73%)
Specificity	98.75% (95% CI, 93.23% -99.97%)
PPV	92.31% (95% CI, 62.64% -98.85%)
NPV	95.18% (95% CI, 89.42% -97.88%)
LR+	60.00% (95% CI, 8.38 – 429. 45%)
LR-	0.25 (95% CI, 0.11 - 0. 59)
RR	19.15 (95% CI, 7.26 – 50.47)
Accuracy	94.79 (95% CI, 88.26% -98.29%)

Overall diagnostic performance of fetal fibronectin test in symptomatic woman as shown by sensitivity, specificity and others.