SARS-CoV-2 Induces Expression of Cytokine and MUC5AC/5B in Human Nasal Epithelial Cell through ACE 2 Receptor

Figure 6

The effects of ACE2 receptor inhibitor and dexamethasone on spike protein RBD induced MUC5AC/5B protein production in the cultured human nasal epithelial cell in PAS stain and immunofluorescence staining stain. ACE2 inhibitor and dexamethasone significantly decreased the increasement of MUC5AC (green) and MUC5B (red) protein production in PAS stain and immunofluorescence staining. Sp. RBD: spike protein receptor binding protein; PAS: periodic acid-Schiff staining; ACE2 I: angiotensin converting enzyme 2 receptor inhibitor; Dexa: dexamethasone.