Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-κB and MAPK Pathways in LPS-Stimulated BV-2 Microglia

Figure 4

Effects of BA on TLR4 pathways in LPS-stimulated BV-2 microglia. The expression levels of TLR4 (a, b), MyD88 (c, d), IRAK4 (e, f), and IRAK1 (g, h) were analyzed by Western blot. BV-2 was pretreated with BA (2.5-22.5 μM) for 1 h before being stimulated with 0.1 μg/mL LPS for different times (12 h for TLR4 and MyD88 and 20 min for IRAK4 and IRAK1). Results were presented as (). ^### vs. control; , , and vs. LPS.

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