[Retracted] A Comprehensive Review of Performance of Next-Generation Sequencing Platforms

Table 3

Comparison of various Ion Torrent NGS instruments [33].

Methods/applications	Ion GeneStudio S5 System	Ion GeneStudio S5 Plus System	Ion GeneStudio S5 Prime System	Ion PGM 314	Ion PGM 316	Ion PGM 318	Ion Torrent GeneXus
Major applications	ES, TCS, EP, TGS, and sWGS (microbes)			TS (DNA/RNA), CNV, sRNA sequencing, de novo MICS, ChIP-seq, MA, SNP verification, and GbS			WGS, WES, TGS
Run time (hours)	4.5–21.5	3-20	3-10	2.3-3.7	3.0-4.9	4.4-7.3	2.5
Maximum output	15 Gb	30 Gb	50 Gb	300–100 Mb	300 Mb–1 Gb	600 Mb–2 Gb	15 Gb
Maximum reads per run	2-80 million	2-130 million	2-130 million	400–550 thousand	2–3 million	4–5.5 million	12-15 million
Maximum read length	200-600 bp	200-600 bp	200-600 bp	200-400 bp	200-400 bp	200-400 bp	200
Compatible chips	Ion 510, 520, 530, 540 chips	Ion 510, 520, 530		Ion 314 Chip V2 or Ion 314 Chip v2 BC	Ion 316 Chip V2 or Ion 316 Chip v2 BC	Ion 318 Chip V2 or Ion 318 Chip v2 BC	Ion Torrent GX5 Chip
Max. data quality