[Retracted] A Comprehensive Review of Performance of Next-Generation Sequencing Platforms

Table 7

Comparison of various high-performing sequencing instruments.

Manufacturer	Read length	Data output	Max. run time (hours)	Chemistry	Key applications
Illumina (NovaSeq 6000)	300 PE	6 Tb (6000 Gb)	44	Sequencing by synthesis	SS-WGS and TGS, TGEP, 16sMGS, WES, SCP, LS-WGS, CA, MS, MGP, CFS, LBA
Thermo Fisher Scientific Ion Torrent (Ion GeneStudio S5 Prime)	600 SE	50 Gb	12	Sequencing by synthesis	WGS, WES, TGS
GenapSys (16 chips)	150 SE	2 Gb	24	Sequencing by synthesis	TS, SS-WGS, GEV, 16S rRNA sequencing, sRNA sequencing, TSCAS
QIAGEN (GeneReader)	100 SE	Not available	Not available	Sequencing by synthesis	Cancer research and identifying mutations
BGI/Complete Genomics	400 SE	6 Tb (6000 Gb)	40	DNA nanoball	Small and large WGS, WES and TGS
PacBio (HiFi Reads)	25 Kb	66.5 Gb	30	Real-time sequencing	DN sequencing, FT, identifying ASI, mutations, and EPM
Nanopore (PromethION)	4 Mb	14 Tb (14000 Gb)	72	Real-time sequencing	SV, GS, phasing, DNA and RNA base modifications, FT, and isoform detection

Performance comparison is given as per manufacturer’s description. Applications by all sequencers of the respective manufacturer are listed. Full names are given in Abbreviations.