Phytochemistry and Biological Properties of Salvia verbenaca L.: A Comprehensive Review

Table 5

Anticancer effects of S. verbenaca.

Plant part	Tested extract	Cell lines	Major results	Ref.
Leaves	Ethyl acetate	Human breast adenocarcinoma	IC50:  μg/mL	[7]
Aerial parts	Methanol	Human colon adenocarcinoma	LC50: 60.4 μg/mL	[15]
		Human hepatoblastoma	LC50: 68.9 μg/mL
		Human breast cancer cells	LC50: 43.1 μg/mL
		Human pancreatic carcinoma	LC50: 42.2 μg/mL
Aerial parts	Hexane	Human embryonal rhabdomyosarcoma cancerous cell lines	IC50:  μg/mL	[16]
		Vero (monkey kidney cancerous cell lines)
Aerial parts	Ethyl acetate	Human embryonal rhabdomyosarcoma cancerous cell lines		[16]
		Vero (monkey kidney cancerous cell lines)	IC50:  μg/mL
Aerial parts	n-Butanol	Human embryonal rhabdomyosarcoma cancerous cell lines		[16]
		Vero (monkey kidney cancerous cell lines)
Aerial parts	Methanol and chloroform	Breast adenocarcinoma	IC50:  μg/mL	[17]
		Colon adenocarcinoma	IC50:  μg/mL
		Glioblastoma	IC50 was not calculated
		Human kidney epithelial cell line	IC50:  μg/mL
Leaves	Methanol	Monkey kidney cells	CC50: 64 μg/mL	[18]
		Human larynx cancer cells
Roots	Methanol	Human monocytic leukemia cell line	70% of apoptosis and 30% of viable cells at a 1000 μg/mL concentration	[23]
Aerial parts	Essential oils	Human melanoma cell line		[19]