Phytochemistry and Biological Properties of Salvia verbenaca L.: A Comprehensive Review

Table 7

Other biological activities of S. verbenaca.

Activity	Part used	Extracts	Experiment	Major results	Ref.
Antihemolytic	Aerial part	Ethyl acetate	2,2-Azobis (2-amidinopropane) dihydrochloride induces erythrocyte oxidative hemolysis (AAPH)	HT50: 165 min	[21]
		Crude		HT50: 125.1 min
		Chloroform		HT50: 111.5 min
		Aqueous		HT50: 111.5 min
Xanthine oxidase inhibition	Aerial part	Chloroform	Colorimetric approach based on uric acid generation at 295 nm in the presence of 100 mM xanthine in phosphate buffer	IC50:  mg/mL
		Ethyl acetate		IC50:  mg/mL
		Crude		IC50:  mg/mL
		Aqueous		IC50:  mg/mL
Porcine liver carboxylesterase inhibition	Aerial part	Aqueous methanol	Enzyme inhibition by spectrophotometric assay	CE (carboxylesterase) inactivation with a and a Ki value of 38 Mm	[12]
Healing of burns	Leaves	Hexane	Second-degree burn injury induced by a hot metal cylinder in rats	Accelerated healing process with 44.34%	[16]
		Ethyl acetate		Accelerated healing process with 47.55%
		n-Butanol		Accelerated healing process with 49.16%
Anticholinesterases	Aerial part	Methanol	Cholinesterase inhibition	Inhibition effect of AChE at 100 μg/mL	[13]
Anti-α-amylase			α-Amylase inhibition	IC50:  μg/mL
Anti-α-glucosidase			α-Glucosidase inhibition
Immunomodulatory	Aerial parts	Methanol	Phagocytic activity used carbon clearance rate test	Significantly increased phagocytic index () at a dose of 200 mg/kg; Increased corrected phagocytic index ()	[14]