Phytochemistry and Biological Properties of Salvia verbenaca L.: A Comprehensive Review

Table 8

Toxicological studies of S. verbenaca.

Activities	Part used	Extract	Experimental approach	Major results	Ref.
Acute oral toxicity	Aerial parts	n-Butanol, hexane, ethyl acetate	Orally delivered at a dose of 2000 mg/kg in a volume of 0.25 mL per 20 g of body weight to mice and examined for 14 days	body weight	[64]
Acute dermal toxicity	Aerial parts	Hexane, ethyl acetate, n-butanol	For 14 days, daily topical application of S. verbenaca extracts at a dose of 2000 mg/kg body weight	There are no adverse effects, behavioral problems, or fatalities	[64]
Subchronic dermal toxicity	Aerial parts	Hexane, ethyl acetate, n-butanol	For 28 days, daily topical application of S. verbenaca extracts at a dose of 2000 mg/kg body weight	There are no harmful symptoms or changes in the amount of water or food consumed; There is no lethality; There is no change in the parameters of fasting blood circulation; There were no morphological alterations in the main vital organs investigated	[64]