Biochemical Characterization of Different Chemical Components of Parthenium hysterophorus and Their Therapeutic Potential against HIV-1 RT and Microbial Growth
Table 3
Anti-HIV-1 RT activities of P. hysterophorus leaves extracts prepared at high temperature and low (room temperature) temperatures.
Plant name and part
Solvents
Extract (mg/mL)
Inhibition of activity (%)
IC50 (mg/mL)
P. hysterophorus leaves
Hexane (HT)
0.083
11
0.44
0.166
24
0.332
34
0.664
70
Ethyl acetate (HT)
0.083
8
0.55
0.166
17
0.332
29
0.664
60
Methanol (HT)
0.083
4
ND
0.166
7
0.332
15
0.664
25
Aqueous (HT)
0.083
11
0.40
0.166
25
0.332
47
0.664
83
Hexane (RT)
0.083
9
0.65
0.166
19
0.332
26
0.664
45
Ethyl acetate (RT)
0.083
14
0.34
0.166
31
0.332
52
0.664
93
Methanol (RT)
0.083
14
ND
0.166
14
0.332
30
0.664
67
Aqueous (RT)
0.083
51
0.081
0.166
87
0.332
100
#ND: not determined; RT: room temperature; HT: high temperature.