Biochemical Characterization of Different Chemical Components of Parthenium hysterophorus and Their Therapeutic Potential against HIV-1 RT and Microbial Growth

Table 3

Anti-HIV-1 RT activities of P. hysterophorus leaves extracts prepared at high temperature and low (room temperature) temperatures.

Plant name and part	Solvents	Extract (mg/mL)	Inhibition of activity (%)	IC50 (mg/mL)
P. hysterophorus leaves	Hexane (HT)	0.083	11	0.44
		0.166	24
		0.332	34
		0.664	70
	Ethyl acetate (HT)	0.083	8	0.55
		0.166	17
		0.332	29
		0.664	60
	Methanol (HT)	0.083	4	ND
		0.166	7
		0.332	15
		0.664	25
	Aqueous (HT)	0.083	11	0.40
		0.166	25
		0.332	47
		0.664	83
	Hexane (RT)	0.083	9	0.65
		0.166	19
		0.332	26
		0.664	45
	Ethyl acetate (RT)	0.083	14	0.34
		0.166	31
		0.332	52
		0.664	93
	Methanol (RT)	0.083	14	ND
		0.166	14
		0.332	30
		0.664	67
	Aqueous (RT)	0.083	51	0.081
		0.166	87
		0.332	100

^#ND: not determined; RT: room temperature; HT: high temperature.