Biochemical Characterization of Different Chemical Components of Parthenium hysterophorus and Their Therapeutic Potential against HIV-1 RT and Microbial Growth

Table 4

Anti-HIV-1 RT activities of P. hysterophorus flowers extracts prepared at high temperature and low temperatures.

Plant name and part	Solvent	Extract concentration (μg)	Activity lost (% inhibition)	IC50 (mg/mL)
P. hysterophorus flowers	Ethyl acetate (HT)	0.083	15	0.31
		0.166	35
		0.332	56
		0.664	100
	Methanol (HT)	0.083	8	0.47
		0.166	17
		0.332	32
		0.664	67
	Aqueous (HT)	0.083	0	ND
		0.166	0
		0.332	9
		0.664	15
	Ethyl acetate (RT)	0.083	8	0.40
		0.166	18
		0.332	44
		0.664	78
	Methanol (RT)	0.083	5	ND
		0.166	10
		0.332	25
		0.664	47
	Aqueous (RT)	0.083	3	ND
		0.166	18
		0.332	16
		0.664	25

^#ND: not determined; RT: room temperature; HT: high temperature.