Research Article

CD96 Downregulation Promotes the Immune Response of CD4 T Cells and Associates with Ankylosing Spondylitis

Table 1

Clinical characteristics and laboratory features of patients with AS and healthy controls.

Cohort ICohort II
AS ()HC ()AS ()HC ()

Age (years) (20–52) (21–47)0.4268 (18–56) (20–53)0.3789
Sex no. (%)16 M/3 F11 M/4 F0.672210 M/3 F11 M/3 F0.918
Disease duration (years) (0.6 to 35) (0.5–37)
Extra-articular manifestations (%)5 (26)4 (33.3)
Peripheral arthritis (%)6 (31.5)5 (41.7)
BASDAI (0–100) (0.4–94) (0.4–94)
BASFI (0–100) (0–92) (0–92)
HLA-B27+ (%)15 (78.9)10 (83.3)
ESR (mm/h) (1–163) (1–163)
CRP (mg/L) (0 to 350) (0–350)

Data are expressed as the (range). The Mann–Whitney test was used to compare the age, and the chi-square test was used to compare sex between the two groups. BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing Spondylitis Functional Index; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate.