Research Article
Systematic Review and Network Meta-analysis of Acupuncture Combined with Massage in Treating Knee Osteoarthritis
Table 1
Basic characteristics of included studies.
| Included studies | Mean age (years) | Sample size (M/F) | Mean disease duration (year) | Interventions | Duration/day | Follow-up or not | Outcome measures | T | C | T | C | T | C | T | C |
| Ye et al. [26] | | | 23/23 | 24/22 | | | Electrothermal needle+loosening | Loosening | 4 weeks | No | ①④ | Ye et al. [27] | | | 18/29 | 20/25 | | | Heating needle+Maitland | Maitland | 4 weeks | No | ①④ | Zhou [28] | 40~70 | 40~70 | 20/30 | 20/30 | 14 d~7 years | 19 d~6 years | Float needle+tuina | Tuina | 14 d | No | ① | Chao et al. [29] | | | 3/18 | 5/16 | months | months | Fire needle+Meridian-sinew manipulation | Meridian-sinew manipulation | 2 weeks | Yes | ②④ | Lan [30] | | | 33/27 | 35/25 | — | — | Silver needle+tuina | Tuina | 2 weeks | No | ①③ | Duning [31] | | | 7/43 | 6/44 | | | Beryllium needle+tuina | Tuina | 20 d | No | ① | Jiang et al. [32] | | | 13/37 | 9/41 | months | months | Electroacupuncture+tuina | Tuina | 30 d | No | ① | Hongyan et al. [33] | | | 25/35 | 20/30 | | | Warm needling+tuina | Tuina | 20 d | No | ①② | Yuanhong et al. [34] | | | 11/19 | 13/17 | | | Warm needle+Maitland | Maitland | 4 weeks | No | ②③ | Wang [35] | | | 23/55 | 19/59 | | | Warm needling+tuina | Tuina | 20 d | No | ①②③ | Huangke [36] | 35~85 | 35~85 | 36 | 36 | — | — | Warm needling+tuina | Tuina | 20 d | No | ①②③ | Huang et al. [37] | | | 39/81 | 78/22 | | | Warm needling+tuina | Tuina | 20 d | No | ①②③ | Qian et al. [38] | | | 14/18 | 13/19 | months | months | Warming needle+loosening | Loosening | 20 d | No | ①⑤ | Chen [39] | | | 23/17 | 25/15 | | | Warm needling+tuina | Tuina | 30 d | Yes | ①② | Guan [40] | | | 25/30 | 27/28 | | | Warm needling+tuina | Tuina | 4 weeks | No | ① | Qiao [41] | | | 19/31 | 17/25 | | | Warm needling+tuina | Tuina | 4 weeks | No | ①⑤ | Zhang et al. [42] | | | 13/18 | 12/19 | —————— | —————— | Needle knife + Tuina | Tuina | 14d | No | ①②③ | Guibo and Mao [43] | | | 20/20 | 22/18 | | | Needle knife+tuina | Tuina | 2 weeks | No | ① | Wang and Lang [44] | | | 16/21 | 19/19 | | | Needle knife+Maitland | Maitland | 4 weeks | Yes | ①②③ | Wang and Lang [45] | | | 33/40 | 32/35 | months | months | Needle knife+tuina | Tuina | 3 weeks | No | ①② | Ma [46] | | | 12/23 | 13/22 | | | Needle knife+tuina | Tuina | 14 d | No | ②③ | Liangi [47] | 43~64 | 47~63 | 13/17 | 12/18 | 3 months~15 years | 2 months~10 years | Needle knife+tuina | Tuina | 10 d | No | ① | Liao [48] | | | 14/26 | 17/23 | 8 months~18 years | 8 months~18 years | Common acupuncture+tuina | Tuina | 28 d | No | ①② | Chao [49] | | | 15/25 | 14/22 | | | Common acupuncture+tuina | Tuina | 20 d | No | ① | Gao [50] | | | 18/22 | 19/21 | — | — | Common acupuncture+tuina | Tuina | 30 d | No | ⑤ | Dong et al. [51] | | | 15/25 | 17/23 | | | Common acupuncture+Dong’s massage | Dong’s massage | 20 d | No | ①②④ | Wang and Ma [52] | | | 12/23 | 16/19 | 2.0 ± 1.8 | | Catgut embedding needle knife+tuina | Common acupuncture | 3 weeks | No | ①② | Lin et al. [53] | | | 19/31 | 22/28 | | | Warm needling + Tuina | Common acupuncture | 14 d | No | ① | Li [54] | | | 17/15 | 14/18 | months | months | Warm needling+tuina | Common acupuncture | 30 d | No | ①②④ | Xiong et al. [55] | | | 19/27 | 21/24 | | | Common acupuncture+tuina | Common acupuncture | 20 d | No | ①②④⑤ | Huang et al. [56] | | | 12/18 | 13/17 | | | Common acupuncture+tuina | Common acupuncture | 20 d | No | ① | Ding [57] | | | 9/17 | 12/18 | | | Common acupuncture+tuina | Common acupuncture | 8 weeks | No | ②③ | Chen et al. [58] | | | 14/17 | 15/16 | | | Electroacupuncture+Wei’s maneuver | Electroacupuncture | 6 weeks | No | ① | Ma and Wu [59] | | | 17/25 | 16/26 | — | — | Electroacupuncture+tuina | Electroacupuncture | 3 weeks | No | ①②③ | Zeng [60] | | | 19/11 | 18/12 | | | Needle knife+tuina | Needle knife | 4 weeks | No | ② | Li and Zhang [61] | | | 22/28 | 21/29 | | | Needle knife+tuina | Needle knife | 3 weeks | Yes | ①② | Zhu [62] | | | 23/28 | 24/27 | | | Needle knife+tuina | Needle knife | 4 weeks | No | ① | Li [63] | | | 19/46 | 20/45 | | | Warm needling+tuina | Warm needling | 14 d | No | ①②③ | Shen et al. [64] | | | 39/71 | 42/68 | | | Warm needling+tuina | Warm needling | 12 d | No | ①② | Zhou et al. [65] | | | 14/16 | 13/17 | | | Warm needling+tuina | Warm needling | 14 d | No | ①② | Zhou et al. [66] | | | 7/21 | 8/21 | | | Warm needling+tuina | Warm needling | 4 weeks | No | ①②④⑤ | Xiong and Chen [67] | | | 37/43 | 40/38 | | | Needle knife+tuina | Electroacupuncture | 3 weeks | No | ①②③ | Zheng and Dong [68] | | | 18/14 | 17/15 | | | Fire needling+tuina | Warm needling+tuina | 14 d | No | ①② | Wang et al. [69] | | | 10/14 | 8/16 | | | Warm needling+tuina | Common acupuncture+tuina | 30 d | No | ②③ | Lu et al. [70] | | | 37/46 | 38/44 | | | Needle knife+tuina | Common acupuncture+tuina | 3 weeks | No | ①③ | Wang and Liu [71] | | | 21/24 | 18/27 | months | months | Needle knife+tuina | Common acupuncture+tuina | 3 weeks | No | ② | Chen et al. [72] | | | 18/22 | 18/22 | months | months | Needle knife+tuina | Common acupuncture+tuina | 3 weeks | Yes | ① | Zhang et al. [73] | | | 18/24 | 20/24 | | | Silver needling+tuina | Silver needle | 3 weeks | Yes | ④⑤ | | 19/30 | | Tuina | Zhang et al. [74] | | | 22/8 | 23/7 | | | Common acupuncture+tuina | Common acupuncture | 4 weeks | No | ①② | | 18/12 | | Tuina |
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T: test group; C: control group; —: it was not mentioned. ①Total effective rate. ②VAS. ③Lysholm. ④Total WOMAC. ⑤WOMAC stiffness and joint function.
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