Research Article

The Effect of Oral Mucosal Mesenchymal Stem Cells on Pathological and Long-Term Outcomes in Experimental Traumatic Brain Injury

Table 1

Neurological severity score.

Point

Motor tests
Raising rat by the tail (normal =0; maximum =3)
Flexion of forelimb1
Flexion of hind limb1
Head moved >10° to vertical axis within 30 s1
Placing rat on the floor (normal =0; maximum =3)
Normal walk0
Inability to walk straight1
Circling toward the paretic side2
Fall down to the paretic side3
Sensory tests (normal =0; maximum =2)
Placing test (visual and tactile test)1
Proprioceptive test (deep sensation, pushing the paw against the table edge to stimulate limb muscles)2
Beam balance tests (normal =0; maximum =6)
Balances with steady posture0
Grasps side of beam1
Hugs the beam and one limb falls down from the beam2
Hugs the beam and two limbs fall down from the beam, or spins on beam (>60 s)3
Attempts to balance on the beam but falls off (>40 s)4
Attempts to balance on the beam but falls off (>20 s)5
Falls off: no attempt to balance or hang on to the beam (<20 s)6
Reflexes absent and abnormal movements (normal =0; maximum =4)
Pinna reflex (head shake when touching the auditory meatus)1
Corneal reflex (eye blink when lightly touching the cornea with cotton)1
Startle reflex (motor response to a brief noise from snapping a clipboard paper)1
Seizures, myoclonus, myodystony1
Maximum points18