Association of Atopic Dermatitis with Depression and Suicide: A Two-Sample Mendelian Randomization Study

Table 1

The causal effect of AD on major depression.

Method	OR (95% CI)	value		Statistical power
IVW	1.027 (1.004-1.050)	0.020	0.628	0.56
Weighted median	1.015 (0.989-1.042)	0.267	0.319	0.13
MR egger	1.003 (0.940-1.070)	0.929	0.027	0.05
Weighted mode	1.011 (0.978-1.044)	0.539	0.173	0.07
MR PRESSO	1.027 (1.004-1.050)	0.038	0.574	0.53

CI: confidence interval; IVW: inverse variance-weighted; MR: Mendelian randomization; OR: odds ratio; SNP: single-nucleotide polymorphism.