Evaluation of Zuo-Gui Yin Decoction Effects on Six CYP450 Enzymes in Rats Using a Cocktail Method by UPLC-MS/MS

Figure 3

(a) The mean concentration-time curve of phenacetin in rat (ng/mL). (b) The mean concentration-time curve of bupropion in rats (ng/mL). (c) The mean concentration-time curve of amodiaquine in rats (ng/mL). (d) The mean concentration-time curve of omeprazole in rats (ng/mL). (e) The mean concentration-time curve of dextromethorphan in rats (ng/mL). (f) The mean concentration-time curve of midazolam in rats (ng/mL).

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(b)

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(f)