Network Pharmacology-Based Strategy for Predicting Therapy Targets of Citri Reticulatae Pericarpium on Myocardial Hypertrophy

Table 3

41 potential target genes of CRP therapy for myocardial hypertrophy.

No.	Target	Symbol	Entrez ID
1	Progesterone receptor	PGR	5241
2	Nuclear receptor coactivator 2	NCOA2	10499
3	Nuclear receptor subfamily 3 group C member 2	NR3C2	4306
4	Prostaglandin-endoperoxide synthase 1	PTGS1	5742
5	Estrogen receptor 1	ESR1	2099
6	Prostaglandin-endoperoxide synthase 2	PTGS2	5743
7	Heat shock protein 90 alpha family class B member 1	HSP90AB1	3326
8	Metallo-beta-lactamase domain-containing 2	MBLAC2	153364
9	Protein kinase CAMP-activated catalytic subunit alpha	PRKACA	5566
10	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma	PIK3CG	5294
11	RELA proto-oncogene, NF-KB subunit	RELA	5970
12	AKT serine/threonine kinase 1	AKT1	207
13	BCL2 apoptosis regulator	BCL2	596
14	Mitogen-activated protein kinase 3	MAPK3	5595
15	Mitogen-activated protein kinase 1	MAPK1	5594
16	Caspase 3	CASP3	836
17	Fatty acid synthase	FASN	2194
18	Low-density lipoprotein receptor	LDLR	3949
19	BCL2-associated agonist of cell death	BAD	572
20	Superoxide dismutase 1	SOD1	6647
21	Catalase	CAT	847
22	Peroxisome proliferator-activated receptor gamma	PPARG	5468
23	Apolipoprotein B	APOB	338
24	3-Hydroxy-3-methylglutaryl-CoA reductase	HMGCR	3156
25	Cytochrome P450 family 19 subfamily A member 1	CYP19A1	1588
26	Glutathione S-transferase pi 1	GSTP1	2950
27	UDP glucuronosyltransferase family 1 member A1	UGT1A1	54658
28	Peroxisome proliferator-activated receptor alpha	PPARA	5465
29	Sterol regulatory element-binding transcription factor 1	SREBF1	6720
30	Glutathione-disulfide reductase	GSR	2936
31	Adiponectin, C1Q and collagen domain containing	ADIPOQ	9370
32	4-Aminobutyrate aminotransferase	ABAT	18
33	Sterol O-acyltransferase 1	SOAT1	6646
34	Sodium voltage-gated Channel alpha subunit 5	SCN5A	6331
35	Potassium voltage-gated Channel subfamily H member 2	KCNH2	3757
36	Coagulation factor VII	F7	2155
37	Potassium calcium-activated channel subfamily M alpha 1	KCNMA1	3778
38	Nitric oxide synthase 2	NOS2	4843
39	Androgen receptor	AR	367
40	Estrogen receptor 2	ESR2	2100
41	Dipeptidyl peptidase 4	DPP4	1803