The Changes in Optic Nerve after Orbital Decompression Surgery for Thyroid Eye Disease and Case Reports of Ischemic Optic Neuropathy
Table 1
Baseline demographics and clinical features of patients with thyroid eye disease and controls.
Between-group comparison
Subgroup analysis: Surgical TEDa
Control
Nonsurgical TED
Surgical TED
value
Non-DON
DON
value
Patients ()
30
30
52
45
11
Eyes ()
60
60
99
83
16
Age (years)
0.057
0.012
Sex (male)
13 (43.3)
9 (30)
23 (43.4)
0.439
17 (37.8)
9 (81.8)
0.020
Hertel exophthalmolmetry (mm)
<0.001
0.560
BROD (%)
NA
49 (49.5)
36 (43.4)
13 (81.3)
0.010
FROD (%)
NA
50 (50.5)
47 (56.6)
3 (18.7)
0.010
Intraocular pressure (mmHg)
<0.001
0.130
LogMAR visual acuity
0.074
0.005
EOM limitation (%)
33 (55)
66 (66.7)
0.220
52 (62.7)
14 (87.5)
0.100
EOM enlargement (%)
47 (78.3)
77 (77.8)
0.987
61 (73.5)
16 (100)
0.040
Mean deviation (dB)
<0.001
<0.001
Abnormal thyroid function (%)
8 (26.7)
20 (37.7)
0.400
16 (35.6)
4 (36.4)
0.999
Preoperative clinical activity score
1 (0-2)
1 (0-7)
<0.001
1 (0-7)
2 (0-4)
0.310
aFour patients had one eye in the non-DON group and the other eye in the DON group. BROD: bone removal orbital decompression; DON: dysthyroid optic neuropathy; EOM: extraocular muscle; FROD: fat-removal orbital decompression; LogMAR: logarithm of the minimum angle of resolution; NA: not applicable; TED: thyroid eye disease; ; median: range; number: percent. Significant values are shown in bold.
