Exploring the Prognosis of Breast Cancer with Synchronous Distant Nonregional Lymph Node Metastasis and Establishing a Predictive Model: A Population-Based Study
Table 2
Baseline characteristics of breast cancer patients with SDLNM.
Characteristic
Training cohort ()
Validation cohort ()
value
Age (%)
0.570
≤50 y
136 (32.7)
82 (29.7)
51-65 y
175 (42.1)
127 (46.0)
66-80 y
105 (25.2)
67 (24.3)
Race (%)
0.716
White
294 (70.7)
187 (67.8)
Black/AI
78 (18.8)
57 (20.7)
Asian
44 (10.6)
32 (11.6)
Marriage (%)
0.555
Married
210 (50.5)
133 (48.2)
Single and unknown
206 (49.5)
143 (51.8)
Histology (%)
0.661
IDC
332 (79.8)
224 (81.2)
Non-IDC
84 (20.2)
52 (18.8)
SBR grade (%)
0.455
Grade 3
206 (49.5)
129 (46.7)
Grade 1-2
113 (27.2)
71 (25.7)
Unknown
97 (23.3)
76 (27.5)
T stage (%)
0.477
T0-1
66 (15.9)
36 (13.0)
T2
116 (27.9)
91 (33.0)
T3
65 (15.6)
42 (15.2)
T4
169 (40.6)
107 (38.8)
N stage (%)
0.124
N0
47 (11.3)
17 (6.2)
N1
158 (38.0)
108 (39.1)
N2
44 (10.6)
36 (13.0)
N3
167 (40.1)
115 (41.7)
Subtype (%)
0.367
Luminal A
167 (40.1)
121 (43.8)
Luminal B
74 (17.8)
53 (19.2)
Her2 + HR-
58 (13.9)
41 (14.9)
TNBC
117 (28.1)
61 (22.1)
Surgery (%)
0.366
None
154 (37.0)
117 (42.4)
Lumpectomy
63 (15.1)
38 (13.8)
Mastectomy
199 (47.8)
121 (43.8)
Radiotherapy (%)
0.937
Yes
148 (35.6)
99 (35.9)
No
268 (64.4)
177 (64.1)
Chemotherapy (%)
0.247
Yes
353 (84.9)
225 (81.5)
No
63 (15.1)
51 (18.5)
Status (%)
0.708
Alive
264 (63.5)
179 (64.9)
Dead
152 (36.5)
97 (35.1)
AI: American Indian; Her2: human epidermal growth factor receptor type 2; HR: hormone receptor; IDC: infiltrating duct carcinoma; SBR grade: Scarff-Bloom-Richardson grading system; SDLNM: synchronous isolated distant lymph node metastasis; TNBC: triple-negative breast cancer.
