Research Article
Silencing the ADAM9 Gene through CRISPR/Cas9 Protects Mice from Alcohol-Induced Acute Liver Injury
Figure 9
The influence of alcohol on the expression of ADAM9, HSP27, HSP70, PCNA, Bax, Bcl-2, caspase-3, VEGF, and p-STAT3 in the liver of mice 24 h after alcohol treatment. (a) Western blotting results. The expression levels of (b) ADAM9, (c) HSP27, (d) HSP70, (e) PCNA, (f) Bax, (g) Bcl-2, (h) caspase-3, (i) VEGF, and (j) p-STAT3 quantified with the Gel-Pro Analyzer 4.0 software (Media Cybernetics Inc.). Band intensities normalized to β-actin. AU = arbitrary unit. and : significant differences between the positive control or experimental group and the negative control group. ## and #: significant differences between the experimental and positive control groups.
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