Research Article

Mitochondrial Haplogroup Classification of Ancient DNA Samples Using Haplotracker

Figure 1

HG tracking flowchart describing a strategy for the use of Haplotracker to track HG confirmation or subhaplogrouping. If there is more than one HG in Rank Group 1 after HG prediction using CR sequences, the narrowing down of the HGs in Rank Group 1 is attempted first. If more than one scored HG (), it is preferable to track the HGs with scores first. They can be differentiated using specific variants on the server. Then, further narrowing down of the HGs can be conducted if needed. If there are too many HGs to track, differentiation between the top five scored HGs or rank group MRCAs can be conducted. Tracking can be repeated several times to confirm the HGs or track sub-HGs. Tracking ends by verifying the MRCA of Rank Group 1 by differentiating between the rank group MRCAs. HG: haplogroup; CR: control region; MRCA: most recent common ancestor.