Identification of Key Genes Associated with Endothelial Cell Dysfunction in Atherosclerosis Using Multiple Bioinformatics Tools

Figure 10

(a, d) Wound healing assay in all groups. (a) Migration distance of HCAECs in different conditions. (d) Relative quantitative comparison of healing speed analyses mentioned in (a). (b, e) Transwell migration assay in all groups. (b) Representative photomicrographs showing migrating cells in different conditions. (e) Quantification of number of migrating cells demonstrated that overexpression of RAB5A promoted HCAEC migration function (/group). (c, f) Tube formation assay. (c) Representative photomicrographs showing tube formation of HCAECs in different conditions. (f) Quantification of HCAEC tube junction numbers demonstrated that overexpression of RAB5A ameliorated HCAECs to form capillary-like structures (/group). , compared to the HCAEC group; ^#, compared to the HCAEC-RAB5A overexpression group.

(a)

(b)

(c)

(d)

(e)

(f)