Identification of Key Genes Associated with Endothelial Cell Dysfunction in Atherosclerosis Using Multiple Bioinformatics Tools

Figure 4

Identification and verification of key genes. (a, b) The comparison of hub gene expression between normal and disease groups. Four key genes (CTTN, ITGB1, MMP9, and RAB5A) were significantly different in the two conditions (GSE28829: CTTN (), ITGB1 (), MMP9 (), and RAB5A (); GSE43292: CTTN (), ITGB1 (), MMP9 (), and RAB5A (). (c, d) The ROC curves for CTTN, ITGB1, MMP9, and RAB5A demonstrating their ability to predict atherosclerosis (GSE28829 and GSE43292, respectively).

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