Research Article

Physicochemical Characterization of In Vitro LDL Glycation and Its Inhibition by Ellagic Acid (EA): An In Vivo Approach to Inhibit Diabetes in Experimental Animals

Table 1

Characterization of ellagic acid- (EA-) treated MG glycated LDL in vitro.

CharacterizationNative LDLMG-LDLMG-LDL + 80 μM EAMG-LDL + 130 μM EAMG-LDL + 180 μM EAMaximum % inhibition by EA (180 μM)

UV-absorbance (280 nm)56%
Fluorescent AGEs70%
Ketoamines nM mg−152%
Carbonyl content (CC) nM mg−162%
Intrinsic fluorescence (A.U.)40%

Data shown in table represents average of three experiments. The values represent the . The and values differ significantly with MG-LDL.