Dexmedetomidine Alleviates Lung Oxidative Stress Injury Induced by Ischemia-Reperfusion in Diabetic Rats via the Nrf2-Sulfiredoxin1 Pathway

Table 1

The indices of blood gas analysis (, ).

	Group	T0	T1	T2	T3
PaO2/FiO2 (mmHg)	CS group
	DS group
	CIR group		^#	^#	^#
	DIR group		^#△	^#△	^#△
	DIRD group		^#△§	^#△§	^#△§
pH value	CS group
	DS group
	CIR group		^#	^#	^#
	DIR group		^#△	^#△	^#△
	DIRD group		^#△§	^#△§	^#△§
BE value (mmol/l)	CS group
	DS group
	CIR group		^#	^#	^#
	DIR group		^#△	^#△	^#△
	DIRD group		^#△§	^#△§	^#△§
PaCO2 (mmHg)	CS group
	DS group
	CIR group
	DIR group
	DIRD group

T0-T3 represented the baseline, 60 min after ischemia, and 60 min and 120 min after reperfusion, respectively. PaO₂/FiO₂: partial pressure of arterial oxygen (PaO₂)/fraction of inspired oxygen (FiO₂); BE: base excess; PaCO₂: arterial carbon dioxide tension; CS: control+sham; DS: diabetes mellitus+sham; CIR: control+ischemia-reperfusion; DIR: diabetes mellitus+ischemia-reperfusion; DIRD: diabetes mellitus+ischemia-reperfusion+dexmedetomidine. In the DIRD group, the 3 μg/kg of DEX was used. vs. the CS group; ^# vs. the DS group; ^△ vs. the CIR group; ^§ vs. the DIR group.