Dexmedetomidine Alleviates Lung Oxidative Stress Injury Induced by Ischemia-Reperfusion in Diabetic Rats via the Nrf2-Sulfiredoxin1 Pathway

Table 3

Oxidative stress indices (, ).

	8-OHdG (ng/ml supernatant)	MDA (nmol/mg protein)	iNOS (IU/ml supernatant)	GSH-PX (μmol/mg protein)	SOD (U/mg protein)	T-AOC (U/mg protein)
CS group
DS group
CIR group	^#	^#	^#	^#	^#	^#
DIR group	^#△	^#△	^#△	^#△	^#△	^#△
DIRD group	^#△§	^#△§	^#△§	^#△§	^#△§	^#△§

8-OHdG: 8-hydroxydeoxyguanosine; MDA: malondialdehyde; iNOS: inducible nitric oxide synthase; GSH-PX: glutathione peroxidase; SOD: superoxide dismutase; T-AOC: total antioxidative capabilities; CS: control+sham; DS: diabetes mellitus+sham; CIR: control+ischemia-reperfusion; DIR: diabetes mellitus+ischemia-reperfusion; DIRD: diabetes mellitus+ischemia-reperfusion+dexmedetomidine. In the DIRD group, the 3 μg/kg of DEX was used. vs. the CS group; ^# vs. the DS group; ^△ vs. the CIR group; ^§ vs. the DIR group.