Combination of Goniothalamin and Sol-Gel-Derived Bioactive Glass 45S5 Enhances Growth Inhibitory Activity via Apoptosis Induction and Cell Cycle Arrest in Breast Cancer Cells MCF-7

Figure 5

(a) MCF-7 and (b) HMSC cells were treated with GTN at IC₅₀ and 0.5 mg/mL of BG. Cell viability was assessed via the MTT assay. All experiments were done in triplicate, and the data is represented by means and standard deviations. Comparisons between the groups of different treatments were done by using 1-way ANOVA, followed by Tukey’s posttest for multiple comparisons. Not significant is denoted as ns; the significant difference in the treated cells as compared to untreated cells is marked as , , and , whereas the significant difference between GTN and GTN-BG treatments is represented as ⁺, ⁺⁺, and ⁺⁺⁺.

(a)

(b)