Combination of Goniothalamin and Sol-Gel-Derived Bioactive Glass 45S5 Enhances Growth Inhibitory Activity via Apoptosis Induction and Cell Cycle Arrest in Breast Cancer Cells MCF-7

Figure 6

The inhibitory effects of GTN and GTN-BG at IC₂₅, IC₅₀, and IC₇₅ in MCF-7 following 24, 48, and 72 hours of incubation time. All experiments were done in triplicate, and the data is represented by means and standard deviations. The comparisons between the groups were done by using two-way ANOVA, followed by the Bonferroni posttest for multiple comparisons. Significant differences between the treated (DOX, GTN, and GTN-BG) and untreated (UT) groups were marked as , , and , and the significant differences between GTN and GTN-BG treatments were represented as , ⁺⁺, and ⁺⁺⁺.