Research Article
Baicalin Alleviates Thrombin-Induced Inflammation in Vascular Smooth Muscle Cells
Figure 6
Baicalin inhibits VSMC inflammation by suppressing thrombin-induced PAR-1 expression. (a) The expression of PAR-1 mRNA in VSMCs after exposure to 2.5 U/ml thrombin pre-treated with or without baicalin was determined by RT-PCR. (b) Western blot analysis and quantification of PAR-1 protein level in VSMCs stimulated by 2.5 U/ml thrombin after pretreatment with different doses of baicalin. (c) Immunofluorescence microscopy of punctate pattern of PAR-1 localization in VSMCs treated with 2.5 U/ml thrombin with or without baicalin.,, and .
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