Research Article
Computational Clues of Immunogenic Hotspots in Plasmodium falciparum Erythrocytic Stage Vaccine Candidate Antigens: In Silico Approach
Table 3
Prediction results for secondary structures of 14 selected erythrocytic stage P. falciparum antigens, using Garnier–Osguthorpe–Robson (GOR IV) server.
| | Secondary structure | AMA1 | CyRPA | Eba175 | MSP1 | MSP3 | MSP4 | MSP6 | Ralp1 | RESA | Rh5 | Ripr | Ron2 | Sera5 | Sera8 |
| | Alpha helix | 139 (22.35) | 29 (8.01) | 428 (29.83) | 789 (48.14) | 278 (70.56) | 100 (36.76) | 138 (32.32) | 275 (40.62) | 544 (50.70) | 210 (39.92) | 106 (9.76) | 667 (48.72) | 201 (20.16) | 136 (19.71) | | Extended strand | 91 (14.63) | 134 (37.02) | 236 (16.45) | 179 (10.92) | 34 (8.63) | 46 (16.91) | 55 (12.88) | 95 (14.03) | 109 (10.16) | 74 (14.07) | 318 (29.28) | 175 (12.78) | 224 (22.47) | 171 (24.78) | | Random coil | 392 (63.02) | 199 (54.97) | 771 (53.73) | 671 (40.94) | 82 (20.81) | 126 (46.32) | 234 (54.8) | 307 (45.35) | 420 (39.14) | 242 (46.01) | 662 (60.96) | 527 (38.5) | 572 (57.37) | 383 (55.51) |
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