Combination Therapy of Ledipasvir and Itraconazole in the Treatment of COVID-19 Patients Coinfected with Black Fungus: An In Silico Statement

Figure 2

Plots of root-mean-square deviations of each protein-ligand complexes of sixty antiviral compounds with the (a) SARS-CoV-2 spike glycoprotein (PDB 7NEH), (b) protein related to the autophagy (PDB 5YEC), and (c) TLR4 (PDB 5IJC). 1, AMP; 2, ATA; 3, DAR; 4, FOS; 5, IND; 6, LOP; 7, NEL; 8, RIT; 9, SAQ; 10, TIP; 11, DEL; 12, DOR; 13, EFA; 14, ETA; 15, NEV; 16, RIL; 17, ABA; 18, DID; 19, EMT; 20, LAM; 21, STA; 22, TEN; 23, ZID; 24, BIC; 25, DOL; 26, ELV; 27, RAL; 28, FOS; 29, DAN; 30, GRA; 31, PAR; 32, SIM; 33, DAC; 34, LED; 35, OMB; 36, ELB; 37, VEL; 38, PIB; 39, SOF; 40, DAS; 41, BAL; 42, FAV; 43, LAN; 44, OSE; 45, PER; 46, ZAN; 47, RIB; 48, ACI; 49, BRI; 50, FAM; 51, IDO; 52, PEN; 53, VAL; 54, CID; 55, FOS; 56, GAN; 57, ADE; 58, BES; 59, CLE; 60, TEC.

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