Research Article
[Retracted] Identification of Molecular Biomarkers and Key Pathways for Esophageal Carcinoma (EsC): A Bioinformatics Approach
Table 4
Gene Ontology analysis of downregulated DEGs using DAVID functional tools.
| Category | GO ID | Term | Count | % | value |
| BP | GO:0006413 | Translational initiation | 37 | 0.014347 | 4.26E-09 | BP | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 27 | 0.010469 | 1.96E-07 | BP | GO:0006412 | Translation | 50 | 0.019388 | 3.60E-07 | BP | GO:0019083 | Viral transcription | 29 | 0.011245 | 6.66E-07 | BP | GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 30 | 0.011633 | 7.51E-07 | BP | GO:0048245 | Eosinophil chemotaxis | 8 | 0.003102 | 1.64E-06 | BP | GO:0007155 | Cell adhesion | 69 | 0.026755 | 4.88E-05 | BP | GO:0006364 | rRNA processing | 38 | 0.014735 | 1.20E-04 | BP | GO:0002548 | Monocyte chemotaxis | 13 | 0.005041 | 2.75E-04 | BP | GO:0007156 | Homophilic cell adhesion via plasma membrane adhesion molecules | 29 | 0.011245 | 5.11E-04 | Category | | Term | Count | % | value | CC | GO:0031012 | Extracellular matrix | 55 | 0.021326 | 3.51E-07 | CC | GO:0005840 | Ribosome | 37 | 0.014347 | 4.78E-07 | CC | GO:0022625 | Cytosolic large ribosomal subunit | 20 | 0.007755 | 5.24E-06 | CC | GO:0030424 | Axon | 40 | 0.01551 | 3.48E-05 | CC | GO:0005578 | Proteinaceous extracellular matrix | 45 | 0.017449 | 6.17E-05 | CC | GO:0005788 | Endoplasmic reticulum lumen | 35 | 0.013571 | 9.14E-05 | CC | GO:0005747 | Mitochondrial respiratory chain complex I | 14 | 0.005429 | 2.80E-04 | CC | GO:0022627 | Cytosolic small ribosomal subunit | 13 | 0.005041 | 8.53E-04 | CC | GO:0098793 | Presynapse | 15 | 0.005816 | 0.001358 | CC | GO:0015935 | Small ribosomal subunit | 9 | 0.00349 | 0.00193 | Category | | Term | Count | % | value | MF | GO:0003735 | Structural constituent of ribosome | 49 | 0.019 | 1.85E-08 | MF | GO:0008137 | NADH dehydrogenase (ubiquinone) activity | 13 | 0.005041 | 0.001124 | MF | GO:0044822 | Poly(A) RNA binding | 134 | 0.051959 | 0.001979 | MF | GO:0008237 | Metallopeptidase activity | 17 | 0.006592 | 0.002751 | MF | GO:0005201 | Extracellular matrix structural constituent | 15 | 0.005816 | 0.002881 | MF | GO:0003723 | RNA binding | 70 | 0.027143 | 0.004922 | MF | GO:0047555 | 3,5-cyclic-GMP phosphodiesterase activity | 6 | 0.002327 | 0.006619 | MF | GO:0042056 | Chemoattractant activity | 8 | 0.003102 | 0.009717 | MF | GO:0001077 | Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | 34 | 0.013184 | 0.01087 | MF | GO:0008009 | Chemokine activity | 11 | 0.004265 | 0.012935 |
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