Isoflavaspidic Acid PB Extracted from Dryopteris fragrans (L.) Schott Inhibits Trichophyton rubrum Growth via Membrane Permeability Alternation and Ergosterol Biosynthesis Disruption

Table 2

MIC values (μg/mL) of drugs in the absence and presence of sorbitol (0.8 M) and ergosterol (400 μg/mL) against T. rubrum (CMCC(F)T1d).

Drug	Sorbitol			Ergosterol
	Absence	Presence	Control	Absence	Presence
Isoflavaspidic acid PB	20	20	+	20	80
Amphotericin B^a	—	—	+	0.5	8

^aPositive control. (—): amphotericin B was not tested in the sorbitol assay. (+): fungal growth in the presence of sorbitol (0.8 M) and absence of drugs.