Clinical, Serological, and Genetic Characteristics of a Hungarian Myositis-Scleroderma Overlap Cohort
Table 2
Comparison of patients with and without PAH.
SSc-myositis overlap
Patients with PAH
Patients without PAH
value
Demographic data
Number of patients
12
27
—
Male/female
2/10
7/20
ns
ns
ns
dcSSc/lcSSc
4/8
13/14
ns
Number of death (no. of patients/%)
4/10
40
2/17
11.76
ns
Clinical data
ILD (no. of patients/%)
9
75
21
77.78
ns
Arthritis (no. of patients/%)
10
83.33
22
81.48
ns
Raynaud’s phenomenon (no. of patients/%)
12
100
26
96.3
ns
Dysphagia (no. of patients/%)
9
75
17
62.96
ns
Fever (no. of patients/%)
5
41.67
2
7.41
0.0046
Cardiac involvement (no. of patients/%)
10
83.33
6
22.22
0.0008
Calcinosis (no. of patients/%)
5
41.66
3
11.11
0.01146
Claw hand deformity (no. of patients/%)
3
25
3
11.11
0.00016
SD: standard deviation; ILD: interstitial lung disease; PAH: pulmonary arterial hypertension; ns: not significant; stepwise discriminant analysis with Wilks method was performed. Continuous and binary variables were investigated. Significances of the association between PAH and the outcome of the disease were calculated with Fisher’s exact test.
