Remimazolam Requires Less Vasopressor Support during Induction and Maintenance of General Anesthesia in Patients with Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Retrospective Analysis from a Single Center
Table 3
Anesthetic events and the time required. Values are shown as median (interquartile range). A was considered to indicate statistical significance.
Group R/R
Group P/S
Group M/P
value
Induction of anesthesia
Time from medication to loss of consciousness (min)
2.2 [1.7-2.9]
1.5 [1.2-1.8]
2.1 [1.7-2.2]
0.10
Time from medication to less than 60 of Entropy (min)
3.3 [2.6-4.5]
1.7 [1.0-2.8]
3.3 [2.3-3.7]
0.005
Time from medication to tracheal intubation (min)
5.5 [4.4-5.9]
5.0 [4.7-5.8]
5.4 [4.3-6.2]
0.96
End of anesthesia
Time from discontinuation of medication to extubation (min)
11.7 [7.2-13.3]
9.5 [7.0-11.0]
11.8 [11.3-15.1]
0.03
Time from the end of surgery to extubation (min)
11.9 [6.6-18.7]
16.0 [11.2-20.2]
12.9 [8.8-16.0]
0.38
Time from extubation to discharge from operating room (min)
15.0 [9.1-21.5]
17.7 [15.0-20.0]
19.2 [15.5-20.9]
0.42
Awakening from anesthesia
Entropy value when flumazenil is administered
30 [26-36]
—
—
Time from flumazenil administration to Entropy exceeding 90 (min)
