Relationship between Neutrophil Gelatinase-Associated Lipocalin, Eosinophil Cationic Protein, Cytokines, and Atopic Sensitization in Patients with Allergic Diseases
Table 2
Clinical and laboratory characteristics of subjects.
Parameters
Patients ()
Healthy subjects ()
value
Anthropometric parameters
Age (years)
0.485
Sex (male, %)
71 (52.2)
31 (53.4)
0.876
BMI (kg/m2)
0.743
SBP (mmHg)
0.145
Lipocalin
NGAL (ng/mL)
137.5 (97.5–174.0)
69.5 (50.7–110.5)
<0.001
Elevated NGAL (, %)
56 (41.2)
0 (0.0)
<0.001
Allergic parameters
ECP (μg/L)
46.9 (31.2–87.6)
11.7 (3.5–16.4)
<0.001
ECP/Eo ratio
0.24 (0.05–6.21)
0.08 (0.03–0.42)
<0.001
Elevated ECP
110 (80.9)
0 (0.0)
<0.001
tIgE (IU/mL)
351.5 (26.0–872.4)
13.8 (4.5–92.1)
<0.001
sIgE score
3 (2–5)
0 (0–0)
<0.001
Inflammatory markers
hsCRP (mg/dL)
1.24 (0.25–3.79)
0.09 (0.06–0.38)
<0.001
Elevated hsCRP (n, %)
91 (66.9)
0 (0.0)
<0.001
Data are expressed as , median (IQR), or frequency (percentage). BMI: body mass index; SBP: systolic blood pressure; NGAL: neutrophil gelatinase-associated lipocalin; ECP: eosinophil cationic protein; ECP/Eo ratio: ECP/eosinophil count ratio; tIgE: total immunoglobulin E; sIgE: specific IgE; and hsCRP: high-sensitivity C-reactive protein.
