Relationship between Neutrophil Gelatinase-Associated Lipocalin, Eosinophil Cationic Protein, Cytokines, and Atopic Sensitization in Patients with Allergic Diseases

Table 3

NGAL levels in allergic patients with and without systemic inflammation.

Parameters	Allergic patients ()		Healthy subjects ()
	With systemic inflammation ()	Without systemic inflammation ()
Clinical parameters
Age (years)
Sex (male, %)	47 (53.2)	24 (53.3)	31 (53.4)
Laboratory parameters
NGAL (ng/mL)	152.3 (118.5–214.0) ^a,b	86.7 (59.5–132.0)	69.5 (50.7–110.5)
ECP (μg/L)	47.6 (36.1–90.2)^b	41.2 (31.0–86.5)^b	11.7 (3.5–16.4)
ECP/Eo ratio	0.29 (0.08–6.57)^a,b	0.20 (0.04–5.02)^b	0.08 (0.03–0.42)
hsCRP (mg/dL)	2.16 (0.61–4.07)^a,b	0.23 (0.12–0.43)^b	0.09 (0.06–0.38)
tIgE (IU/mL)	365.1 (27.5–891.4)^b	320.7 (23.1–854.6)^b	13.8 (4.5–92.1)
sIgE score	3 (2–5)^b	3 (2–5)^b	0 (0–0)

Data are expressed as , median (IQR), or frequency (percentage). ^aSignificant (), compared with allergic patients without systemic inflammation. ^bSignificant (), compared with healthy subjects. NGAL: neutrophil gelatinase-associated lipocalin; ECP: eosinophil cationic protein; ECP/Eo ratio: ECP/eosinophil count ratio; hsCRP: high-sensitivity C-reactive protein; tIgE: total immunoglobulin E; and sIgE: specific IgE.