Use of Autologous Serum Eye Drops with Contact Lenses in the Treatment of Chemical Burn-Induced Bilateral Corneal Persistent Epithelial Defects

Figure 1

Case presentation. (a and b) Slit-lamp microscopic images of a 78-year-old woman with bilateral nonhealing corneal PEDs measuring  mm on the right eye under fluorescein staining. (c and d) Corneal PEDs measuring  mm on the left eye under fluorescein staining. Mild corneal edema associated with the defects and initial corneal melting at the central lesions is also noted on both eyes. (e and f) Five days after initiating combined silicone–hydrogel CL and 20% ASE treatment, the lesion shows reepithelialization, and no corneal epithelial defect is noted on her right eye. (g and h) The lesion is completely reepithelialized on the left eye after twelve days of combined treatment. After total reepithelialization, the CLs are removed and the ASEs are tapered to four times daily for an additional 2 weeks. No recurrence of the epithelial breakdown is noted during a 3-month posttreatment follow-up.

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