Research Article

Use of Autologous Serum Eye Drops with Contact Lenses in the Treatment of Chemical Burn-Induced Bilateral Corneal Persistent Epithelial Defects

Table 1

Demographic data of the 8 patients of chemical burn-induced bilateral corneal PEDs receiving combined treatments of silicone–hydrogel CLs and 20% autologous serum eye drops.

Case no.Age
(years)
GenderMechanisms of chemical injuriesChemical burn grading
OD
OS
Previous treatment(s) for bilateral PEDsLesion size
(mm)
OD
OS
Time between chemical injuries and start of combined treatments (days)Resolution time (days)
OD
OS
BCVA before combined treatments
OD
OS
Final BCVA
OD
OS

178FAcid burns (salicylic acid)Grade II
Grade III
Topical antibiotic eye drops/ointments; preservative-free artificial tears; pressure patching; ASE treatment alone; CL application alone
875
12
CF/1 m
CF/1 m
20/100
20/200
259MAcid burns (salicylic acid)Grade II
Grade III
Topical antibiotic eye drops/ointments; artificial tears; lubricating gel/ointment; pressure patching; ASE treatment alone; CL application alone
675
12
20/400
CF/1 m
20/40
20/50
369MUnknown drugsGrade II
Grade III
Topical antibiotic eye drops/ointments; preservative-free artificial tears; pressure patching; CL application alone; ASE treatment alone
637
14
CF/1 m
CF/1 m
20/50
20/50
463FAlkali burns (ammonia)Grade III
Grade III
Topical antibiotic eye drops/ointments; artificial tears; lubricating gel/ointment; CL application alone; ASE treatment alone
987
10
CF/1 m
CF/1 m
20/100
20/100
557MAcid burns (sulfuric acid)Grade III
Grade III
Topical antibiotic eye drops/ointments; preservative-free artificial tears; pressure patching; CL application alone; ASE treatment alone
847
7
CF/1 m
CF/1 m
20/50
20/50
652FAcid burns (hydrofluoric acid)Grade II
Grade III
Topical antibiotic eye drops/ointments; preservative-free artificial tears; CL application alone; ASE treatment alone
795
10
20/400
CF/1 m
20/50
20/100
760FAlkali burns (ammonia)Grade III
Grade III
Topical antibiotic eye drops/ointments; preservative-free artificial tears, pressure patching; CL application alone; ASE treatment alone
1157
9
CF/1 m
CF/1 m
20/100
20/100
855MUnknown drugsGrade II
Grade II
Topical antibiotic eye drops/ointments; preservative-free artificial tears; ASE treatment alone; CL application alone
565
6
CF/1 m
CF/1 m
20/50
20/50

Roper-Hall classification for the severity of ocular surface burns. Time since starting combined therapy. Abbreviation: M: male; F: female; OD: right eye; OS: left eye; BCVA: best-corrected visual acuity; CLs: contact lenses; ASE: autologous serum eye drop; CF: counting fingers.