[Retracted] Betamethasone Dipropionate Derivatization, Biotransformation, Molecular Docking, and ADME Analysis as Glucocorticoid Receptor

Table 2

In silico ADME assessment and binding affinities of biotransformed products of betamethasone dipropionate.

Compounds	Binding affinity; kcal/mol	Mol. weight; g/ol	HBA	HBD	TPSA; Å^2	Log	GI absorption	BBB	P-gp substrate	Lipinski violations
1	-10.94	504.59	8	1	106.97	3.36	High	No	Yes	1
2	-10.11	502.57	8	8	103.81	3.11	High	No	Yes	1
3	-11.16	444.49	7	1	97.74	2.64	High	No	Yes	0
4	-12.53	390.45	6	2	91.67	2.23	High	No	Yes	0
5	-11.37	372.43	5	1	71.44	3.65	High	Yes	Yes	0