Ischemic Preconditioning and Postconditioning Protect the Heart by Preserving the Mitochondrial Network

Figure 2

IPC and IPost protects against IRI. (a) Cell death in the H9c2 cardiac cell line following sIR, IPC-sIR, and sI-IPost-R (, ~100 cells per group), and . (b) Representative bright-field and fluorescent images of PI (red panel) and Hoechst (blue panel) staining of H9c2. (c) Cell death in isolated primary adult cardiomyocytes following sIR, IPC-sIR, and sI-IPost-R, (, ~70 cells/field); , , and . (d) Representative bright-field and fluorescent images of PI (red panel) and Hoechst (blue panel) staining of isolated primary adult cardiomyocytes. (e) Myocardial infarct size following IR, IPC-IR, and I-IPost-R, hearts per group; and . (f) Representative image of heart slices of control, post-IR, IPC-R, and I-IPost-R.

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