Long Noncoding RNA LINC01554 Inhibits the Progression of NSCLC Progression by Functioning as a ceRNA for miR-1267 and Regulating ING3/Akt/mTOR Pathway

Figure 6

Both LINC01554 and miR-1267 overexpression modulated the ING3/Akt/mTOR pathway. (a, b) LINC01554 was associated with Akt/mTOR signalling. (c) The expression of ING3 and Akt/mTOR pathway-related proteins (Akt, p-Akt, mTOR, and p-mTOR) was detected via western blotting and quantitated in H23 and H1299 cells treated with pcDNA3.1-LINC01554 and the empty pcDNA3.1 vector. (d) The expression of ING3 and Akt/mTOR pathway-related proteins (Akt, p-Akt, mTOR, and p-mTOR) was detected via western blotting and quantitated in H23 and H1299 cells treated with pcDNA3.1-LINC01554 and the empty pcDNA3.1 vector, miR-1267 mimic, and NC mimic.

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