[Retracted] Identification of Paxillin as a Prognostic Factor for Glioblastoma via Integrated Bioinformatics Analysis

Figure 3

Validation of the identified hub gene. (a) High PXN expression in GBM tissues compared with that in normal brain tissues based on the GEPIA database. (b) Principal component analysis (PCA) of differentially expressed genes (DEGs) between high and low PXN expression samples, as determined according to the median PXN expression levels. (c–f) GBM tissues with higher PXN expression versus normal brain tissues according to the TCGA (combined with GTEx) dataset (c), GSE22866 dataset (d), GSE90598 dataset (e), and a meta-analysis from Oncomine database (f). (g, h) Protein expression levels of PXN in GBM tissues in CPTAC data (g) and immunohistochemical results from the HPA platform (h). Gene expression level (i) and protein expression level (j) of PXN were significantly increased in U251 and U87 cell lines compared with NHA cells. . Data represent ; , vs. NHA.

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