Magnetic Hydrogel for Cartilage Tissue Regeneration as well as a Review on Advantages and Disadvantages of Different Cartilage Repair Strategies
Table 1
Most common polymers for cartilage hydrogel scaffolds and their biological activities.
Polymer
Properties
References
Collagen
It has chondro-inductive properties which lead to a suitable 3-D microenvironment for enhancing MSC chondrogenesis. Collagen can also provide immunomodulatory properties by reducing certain immunogenic effects.
It provides chondro-protective and anti-inflammatory properties to enhance cartilage tissue regeneration. Furthermore, it increased the production of collagen type II.
It improves early-stage chondrogenesis and was proved to repair osteochondral defects in vivo studies. HA interacts with receptors such as CD44 to adjust signal transduction and stem cell differentiation.