Prediction of Solitary Plasmacytoma of Bone in Elderly Patients: A Nomogram and a Risk Classification System for Overall Survival

Table 2

Univariate and multivariate analyses of variables associated with overall survival.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CI)	value	HR (95% CI)	value
Age, year
60-70	Reference		Reference
71-82	1.926 (1.526, 2.432)	≤0.001	1.856 (1.469, 2.345)	≤0.001
>82	4.857 (3.691, 6.492)	≤0.001	4.305 (3.256, 5.692)	≤0.001
Sex
Female	Reference
Male	0.867 (0.707, 1.062)	0.167
Race
Black	Reference
White	0.943 (0.709, 1.255)	0.689
Other	1.269 (0.806, 1.998)	0.304
Marital status
No	Reference		Reference
Yes	0.593 (0.483, 0.727)	≤0.001	0.670 (0.544, 0.824)	≤0.001
Primary site
Trunk	Reference
Extremities	1.117 (0.850, 1.469)	0.427
Facial/skull bone	1.256 (0.902, 1.750)	0.177
Grade
I/II	Reference
III/IV	1.616 (0.679, 3.848)	0.278
Pre-B cell	1.048 (0.533, 2.062)	0.892
Stage
Localized	Reference
Distant	1.055 (0.811, 1.372)	0.690
Surgery		0.083
No	Reference		Reference
Yes	0.802 (0.624, 1.030)		0.902 (0.702, 1.160)	0.422
Chemotherapy
No	Reference
Yes	1.037 (0.810, 1.327)	0.774
Radiotherapy
No	Reference		Reference
Yes	0.599 (0.480, 0.746)	≤0.001	0.695 (0.557, 0.868)	≤0.001